20-01 2006

Imatinib (Gleevec en USA Glyvec en el resto del mundo.)
Al parecer muy útil en varias enfermedades, particularmente leucemia crónica.
Funciona bien en dermatofibrosarcoma protuberans y otras proliferaciones de fibroblastos.



Sustained complete remission of metastatic dermatofibrosarcoma protuberans with imatinib mesylate. Anticancer Drugs. 2005 Apr;16(4):461-6.

Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib J Clin Oncol. 2005 Feb 1;23(4):866-73.

Imatinib mesylate: an attractive alternative in young children with large, surgically challenging dermatofibrosarcoma protuberans.
Pediatr Blood Cancer. 2005 May;44(5):511-5.

Imatinib mesylate inhibits the growth of metastatic lung lesions in a patient with dermatofibrosarcoma protuberans. Br J Dermatol. 2004 Jul;151(1):235-7. Review. No abstract available.

Molecularly targeted treatment for dermatofibrosarcoma protuberans.
Semin Oncol. 2004 Apr;31(2 Suppl 6):30-6. Review.

Good response to treatment with the selective tyrosine-kinase inhibitor imatinib in a patient with metastatic dermatofibrosarcoma protuberans]
Ned Tijdschr Geneeskd. 2003 Oct 18;147(42):2072-6. Dutch.

Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment. Genes Chromosomes Cancer. 2003 May;37(1):1-19. Review.

Jairo Mesa Cock