11-09-2005

Maharan DB et al. TOPICAL 20% KOH. AN EFFECTIVE THERAPEUTIC MODALITY FOR MOLUSCUM CONTAGIOSUM IN CHILDREN. Indian J Dermatol Venereol Leprol. 2003;69(2):175-177.

Es un estudio abierto en 27 niños con moluscos multiples. Usan topicaciones hechas por los padres, de KOH al 20% en cada lesion, en la noche, hasta obtener irritacion o ulceracion superficial (5-7dias) . Reportan resultados del 89% en un promedio de 17 dias.
Un metodo poco traumatico para los niños, bien tolerado, no invasivo, rapido y BARATO.

Angela Seidel Arango
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Double-blind, randomized, placebo-controlled trial of the use of topical 10% potassium hydroxide solution in the treatment of molluscum contagiosum.
Pediatr Dermatol. 2006 May-Jun;23(3):279-81.

(...) recent studies have suggested that potassium hydroxide may be beneficial. This double-blind, randomized, placebo-controlled study compared 10% potassium hydroxide with placebo (normal saline). Twenty patients, aged 2 to 12 years, were recruited. Parents applied a solution twice daily to lesional skin until signs of inflammation appeared. Children were examined by the same observer on days 0, 15, 30, 60, and 90. Seventy percent of children receiving topical potassium hydroxide cleared, compared with 20% in the placebo group (...) potassium hydroxide are as efficacious, with less irritancy.

Jairo Mesa Cock